Urinary hydroxyproline and thyroid disease.
نویسندگان
چکیده
منابع مشابه
Urinary Hydroxyproline Excretion in Orthopedic Disease. Preliminary Report.
The significance of urinary hydroxyproline has not been completely clarified. It appears, however, that this amino acid excretion is correlated with either synthesis or destruction of collagen. Collagen hydroxyproline is reported to be formed by the irreversible hydroxylation of peptid-linked proline and no free hydroxyproline is incorporated directly into this protein. Therefore, the changes o...
متن کاملIntrauterine malnutrition and urinary hydroxyproline excretion.
Both amniotic fluid and urine of newborns contain .hydroxyproline, an amino-acid related to the collagen metabolism and particularly the collagen matrix. Phases of rapid growth of the human body are accompanied by a high collagen turnover resulting in an increased excretion of hydroxyproline in the urine, whereas malnourishment and retarded growth lead to a diminished output [11,15]. In normal ...
متن کاملUrinary hydroxyproline excretion in myelofibrosis.
Urinary hydroxyproline measurements were performed in a group of health volunteers as well as patients with cancer and myelofibrosis. Patients in whom there was no metastatic involvement of bone marrow excreted an amount of hydroxyproline not different from that of the control group. Those who had marrow metastasis produced elevated levels of hydroxyproline; the highest excretions were observed...
متن کاملRelationship between urinary hydroxyproline and growth.
Beginning with the report of Ziff, Kibrick, Dresner, and Gribetz (2), evidence accumulated in recent years has indicated that urinary hydroxyproline excretion reflects collagen metabolism, since collagen is the only protein in the body that contains hydroxyproline in significant amounts (3). Ziff and co-workers, observing that the excretion of this amino acid in peptide form was greater in chil...
متن کاملRelation between Urinary Hydroxyproline and Parathyroid Function.
With the exception of small amounts in elastin, all the hydroxyproline (OHPr) in the body is found in collagen. Evidence has been presented that the urinary peptide-bound OHPr reflects the metabolism of collagen (2-5) except when the dietary intake of gelatin or collagen is excessive. Since a major body depot of collagen is the matrix of bone, it might be anticipated that under some conditions ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5745.404